Peritoneal Dialysis

Peritoneal Dialysis

When kidneys fail to a point where they can no longer sustain safe body function, renal replacement therapy becomes necessary. Most patients are familiar with haemodialysis, which involves coming to a centre three times a week. Fewer know that peritoneal dialysis exists as an alternative, one that can be performed at home, around a patient's own schedule, without the repeated needle insertions or hospital visits that haemodialysis requires. It is not the right choice for everyone. But for many patients, particularly those who are working, caring for a family, or living at a distance from a dialysis centre, it offers a degree of independence that matters considerably.

The peritoneum is a thin membrane that lines the inner wall of the abdomen and covers the organs within it. It has a rich blood supply and acts naturally as a semipermeable barrier, which makes it suitable as a dialysis membrane. In peritoneal dialysis, a sterile fluid called dialysate is introduced into the peritoneal cavity through a soft catheter surgically placed just below the navel, usually in the lower left quadrant of the abdomen. The fluid dwells inside for a set period, during which waste products and excess fluid from the surrounding blood vessels pass across the peritoneal membrane into the dialysate by diffusion and osmosis. The used fluid, now carrying the metabolic waste, is then drained out and replaced with a fresh solution. Each cycle of fill, dwell, and drain is called an exchange.

  • Continuous Ambulatory Peritoneal Dialysis (CAPD)
    This is the manual form. Approximately two litres of dialysate are infused into the peritoneal cavity and allowed to dwell for four to six hours. The exchange is performed four times throughout the day, including once overnight. No machine is involved. Patients learn to perform the exchanges themselves after structured training. Between exchanges, the fluid sits inside the abdomen, and dialysis continues passively while the patient goes about normal activity.
  • Automated Peritoneal Dialysis (APD)
    APD uses a small machine called a cycler that performs multiple fluid exchanges automatically overnight, typically over eight to ten hours while the patient sleeps. During the day, the abdomen may be left empty or with a single daytime dwell depending on the prescription. This option suits patients who prefer to keep their daytime hours entirely free.

Peritoneal dialysis works well for patients who are motivated, have adequate home conditions, and can be trained to manage the procedure safely. It is particularly well-suited for patients with some residual kidney function, elderly patients with cardiovascular instability who may not tolerate the fluid shifts of haemodialysis well, and those living far from a dialysis centre. It is generally not advised for patients with significant abdominal scarring from prior surgeries, active inflammatory bowel disease, or hernias that cannot be repaired before catheter placement. Consult the best peritoneal dialysis doctors in Navi Mumbai at UMC Hospitals for detailed evaluation and care.

Infection is the most serious risk associated with peritoneal dialysis. Peritonitis, infection of the peritoneal cavity, most commonly occurs due to a break in sterile technique during an exchange. Symptoms include cloudy, drained fluid, abdominal pain, and fever. It requires prompt antibiotic treatment and, in severe or recurrent cases, may necessitate catheter removal and temporary switch to haemodialysis.

Strict hand hygiene before every exchange, proper catheter exit site care, and avoiding the exchange in dusty or unclean environments are non-negotiable practices that patients are thoroughly trained on before starting home therapy.

  • Peritoneal dialysis is gentler on the cardiovascular system because fluid removal happens gradually over hours rather than rapidly during a three to four-hour session
  • It preserves residual kidney function longer in many patients compared to haemodialysis
  • It does not require vascular access, meaning no fistula creation or repeated needle insertions
  • Haemodialysis generally provides more efficient waste clearance per session, which matters more in patients with no remaining kidney function
  • Peritoneal dialysis carries a higher risk of peritonitis, while haemodialysis carries higher risks of access-related infections and blood pressure drops during sessions
  • Dietary restrictions differ slightly, with peritoneal dialysis patients often having more liberal fluid allowances but needing to account for glucose absorbed from the dialysate

Patients on peritoneal dialysis absorb glucose from the dialysate continuously, which can contribute to weight gain, elevated triglycerides, and blood sugar fluctuations over time. Dietary guidance focuses on adequate protein intake, roughly 1.2 to 1.5 grams per kilogram of body weight daily, to compensate for protein lost during exchanges. Potassium and phosphate restrictions apply similarly to haemodialysis patients, though the specifics are adjusted based on monthly blood results.

Our Department of Nephrology at UMC Hospitals in Navi Mumbai provides end-to-end peritoneal disease treatment in Navi Mumbai, including surgical catheter placement, structured home training for patients and caregivers, monthly clinical review, and ongoing dietary support through our renal dietitian. Patients are not discharged into home therapy until they and their support person demonstrate confidence with the full exchange procedure. We remain accessible for troubleshooting between visits because with home dialysis, timely guidance matters as much as the initial training.